As a result of cannabidiol’s wide assortment of therapeutic and medical benefits, it has been used as a major ingredient in many health and wellness products. Their effectiveness depends on the CBD concentration contained in them, or in other words, the potency. The most popular item is CBD oil and it is available in different concentrations and can be difficult for a first time user to select the right one. It is believed that high potency CBD oils are good because they can give maximum benefits. But, you should know that CBD oil has a bell-shaped dose-response, i.e. it is, most effective at medium dose. So, what is the impact of potency on the effectiveness of CBD oil?
The Effect Of Potency On CBD Oil Dosage
The potency of CBD oil is the amount of cannabidiol contained in it and it is measured in milligrams (mg). This varies according to the strain of hemp flower from which it is extracted, as well as the type of extract used. For example, a full-spectrum extract contains all the cannabinoids, terpenes, and other natural plant compounds along with CBD. So, a 1000mg product using this type of extract might only contain 50mg of CBD. Besides, they have the entourage effect in which the cannabinoids and other compounds work together to enhance the individual effect of each cannabinoid. Hence, the relation between potency, dosage, and the effects is not linear but dynamic.
However, with CBD isolates, the potency directly influences the dosage and thereby the effects. This is because it is 99% pure cannabidiol and it is most effective at medium dose. You should also know that it is highly potent and should be used where you need the maximum cannabidiol effect in the shortest amount of time. Therefore, high potency CBD oils made from it are used in treating severe skin conditions like psoriasis and eczema.
The Potency Of CBD Oil And Side Effects
As mentioned in the introduction, the potency of CBD oil has a direct effect on its dosage and you should know that it inhibits the action of CYP450 liver enzyme. This is important because it is responsible for the metabolism of pharmaceutical drugs as well as CBD in the liver. As a result, it reduces the efficiency of the liver affecting the duration of the drug action in our body. This, in turn, causes side effects due to unmetabolized medication.
So, when selecting medical CBD oils, understanding the potency is important as it determines the dosage.